Fixed Eruptions: Drug, food, and what more?

Fixed drug eruption (FDE) is a common entity encountered in our day-to-day Cold Cup clinical practice.It is a T-cell-dependent pathway with induction of interferon-gamma-producing CD8+ T-cells in the dermis and epidermis.It is not just a drug that causes a fixed eruption but has also been described with food known as fixed food eruption and also with other agents.The article Gift Sets describes the common causes and pathomechanism of FDE.